Fitness Over Fat: Mortality Risks in Older Adults

By CAFMI From JAMA

Cardiorespiratory Fitness: A Key Mortality Predictor

This study highlights the crucial role of cardiorespiratory fitness (CRF) in predicting mortality among older adults aged 65 and above. In a cohort of 1408 participants without cardiovascular disease, a strong relationship was found between low CRF and higher all-cause mortality risk over an average of six years. Those in the lowest CRF group had more than three times the mortality risk compared to the most fit group, after adjusting for other factors. This finding emphasizes the significance of fitness levels over traditional measures of body fat in assessing health risks in this population.

Adiposity’s Limited Role in Mortality Risk

Contrary to common assumptions, the study found no independent association between measures of adiposity — including body mass index (BMI) and waist circumference — and mortality risk in older adults. These results suggest that simply focusing on weight or fat reduction may not significantly alter mortality outcomes in this age group. Instead, body fat appears less important than physical fitness in influencing longevity, challenging standard approaches in clinical care aimed primarily at weight management for older patients.

Clinical Implications for Primary Care Practice

For primary care clinicians, these findings advocate prioritizing strategies that improve cardiorespiratory fitness among older adults, regardless of their weight status. Exercise interventions aimed at boosting fitness could offer a more effective means of reducing mortality risk than focusing solely on adiposity reduction. Clinicians should consider fitness assessment and counseling as integral parts of care plans for older patients, helping to enhance healthspan and survival. This approach shifts focus toward functional health and cardiovascular conditioning, which has clear benefits for aging populations.


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